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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
LIMK1
All Species:
16.36
Human Site:
T261
Identified Species:
36
UniProt:
P53667
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P53667
NP_002305.1
647
72585
T261
L
E
H
D
P
H
D
T
L
G
H
G
L
G
P
Chimpanzee
Pan troglodytes
XP_001148746
647
72505
T261
L
E
H
D
P
H
D
T
L
G
H
G
L
G
P
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_849646
647
72740
T261
L
E
H
D
P
H
D
T
P
G
H
G
P
G
P
Cat
Felis silvestris
Mouse
Mus musculus
P53668
647
72775
S261
L
E
H
D
P
H
D
S
L
G
H
G
P
V
S
Rat
Rattus norvegicus
P53669
647
72575
S261
L
E
H
D
P
H
D
S
L
G
H
G
P
V
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506118
617
69519
S262
E
G
T
L
R
R
R
S
L
R
R
S
N
S
I
Chicken
Gallus gallus
Q8QFP8
662
74427
A268
E
P
L
P
R
D
L
A
L
P
C
S
P
L
P
Frog
Xenopus laevis
O42565
615
69775
A261
P
S
P
C
A
E
I
A
V
R
R
Q
R
P
V
Zebra Danio
Brachydanio rerio
NP_001036156
648
72664
V264
P
H
D
Q
G
P
S
V
D
H
V
D
G
G
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q8IR79
1257
139286
K323
T
P
G
E
Q
G
T
K
A
R
K
L
R
Q
A
Honey Bee
Apis mellifera
XP_396603
1027
115500
A258
L
T
Y
S
S
P
S
A
A
M
L
T
S
I
S
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.6
N.A.
94.1
N.A.
95.2
95.2
N.A.
53.4
82
72.1
72.9
N.A.
26.8
34.4
N.A.
N.A.
Protein Similarity:
100
99.2
N.A.
96.2
N.A.
96.9
96.9
N.A.
69.4
87
81.1
82.2
N.A.
35.7
43.9
N.A.
N.A.
P-Site Identity:
100
100
N.A.
86.6
N.A.
73.3
73.3
N.A.
6.6
13.3
0
13.3
N.A.
0
6.6
N.A.
N.A.
P-Site Similarity:
100
100
N.A.
86.6
N.A.
80
80
N.A.
13.3
13.3
6.6
13.3
N.A.
6.6
13.3
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
10
0
0
28
19
0
0
0
0
0
10
% A
% Cys:
0
0
0
10
0
0
0
0
0
0
10
0
0
0
0
% C
% Asp:
0
0
10
46
0
10
46
0
10
0
0
10
0
0
0
% D
% Glu:
19
46
0
10
0
10
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
10
10
0
10
10
0
0
0
46
0
46
10
37
0
% G
% His:
0
10
46
0
0
46
0
0
0
10
46
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
10
0
0
0
0
0
0
10
10
% I
% Lys:
0
0
0
0
0
0
0
10
0
0
10
0
0
0
0
% K
% Leu:
55
0
10
10
0
0
10
0
55
0
10
10
19
10
0
% L
% Met:
0
0
0
0
0
0
0
0
0
10
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
10
0
0
% N
% Pro:
19
19
10
10
46
19
0
0
10
10
0
0
37
10
46
% P
% Gln:
0
0
0
10
10
0
0
0
0
0
0
10
0
10
0
% Q
% Arg:
0
0
0
0
19
10
10
0
0
28
19
0
19
0
0
% R
% Ser:
0
10
0
10
10
0
19
28
0
0
0
19
10
10
28
% S
% Thr:
10
10
10
0
0
0
10
28
0
0
0
10
0
0
0
% T
% Val:
0
0
0
0
0
0
0
10
10
0
10
0
0
19
10
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
10
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _